About Us
EN
ENCN
Journal of Medicinal ChemistryJournal Home
The Journal of Medicinal Chemistry发表分子结构与生物活性或作用模式之间关系的相关研究。 The Journal of Medicinal Chemistry publishes studies that contribute to an understanding of the relationship between molecular structure and biological activity or mode of action. Some specific areas that are appropriate include the following: Design, synthesis, and biological evaluation of novel biologically active compounds, diagnostic agents, or labeled ligands employed as pharmacological tools. Molecular modifications of reported series that lead to a significantly improved understanding of their structure-activity relationships (SAR). Routine extensions of existing series that do not utilize novel chemical or biological approaches or do not add significantly to a basic understanding of the SAR of the series will normally not be accepted for publication. Structural biological studies (X-ray, NMR, etc.) of relevant ligands and targets with the aim of investigating molecular recognition processes in the action of biologically active compounds. Molecular biological studies (e.g., site-directed mutagenesis) of macromolecular targets that lead to an improved understanding of molecular recognition. Computational studies that provide fresh insight into the SAR of compound series that are of current general interest or analysis of other available data that subsequently advance medicinal chemistry knowledge. Substantially novel computational chemistry methods with demonstrated value for the identification, optimization, or target interaction analysis of bioactive molecules. Effect of molecular structure on the distribution, pharmacokinetics, and metabolic transformation of biologically active compounds. This may include design, synthesis, and evaluation of novel types of prodrugs. Novel methodology with broad application to medicinal chemistry, but only if the methods have been tested on relevant molecules.
Publishing Model：
ISSN：0022-2623
|EISSN：1520-4804
|Publication Frequency：Twice monthly
|Last updated on 12 Mar 2026 / Current volume： 炆䟕 / Current issue： 逦
More Details
Pharmacy
Impact Factor
Journal Impact Factor(JIF) 2024
炆.躭
Journal Citation Indicator(JCI) 2024
声.躭炆
Web of Science Rank 2024:
。㡶乊胦喊偌穫葤巨, 胦乊枀喊。喊沟嵻欄
# 篫/篫缗
90.97%
Q1
CiteScore Metrics
CiteScore 2024
声声.逦
=
鋺炆声篫䟕 Citation （2022-2024）
鋺蔡蔡逦 Article （2022-2024）
CiteScore Rank 2024
枀㥌憗茡 枀嚷详桧肃聸蠹㥌续
# 声杚/声逦炆
91.67%
Q1
胦肃⻊蠹桧憗⻊囹㥌 胦蠹罒嚷桧嚷鵃蠹
# 缗鋺/声篫篫
86.44%
Q1
